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Updated: Jan 10, 2026

Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies
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多基因分数捕捉了脂肪-心脏代谢风险因子关系的遗传修饰

Kenneth E Westerman1, Julie E Gervis2, Luke J O'Connor3

  • 1Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA, USA; Programs in Metabolism and Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Cell genomics
|November 26, 2025
PubMed
概括

这项研究比较了不同的多基因分数 (PGS) 以预测干预反应. 基于相互作用的PGS (iPGS) 显示出最有前途的方法来识别与BMI相关的心脏代谢风险因素的遗传影响.

关键词:
肥胖症是一种脂肪性.心脏代谢和心脏代谢.基因与环境的相互作用多基因分数的多基因分数

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