一个多动态的低级深度图像之前 (ML-DIP) 为3D实时心血管MRI
Chong Chen1, Marc Vornehm2, Zhenyu Bu1
1Department of Biomedical Engineering, The Ohio State University, Columbus, OH, USA.
概括
一个新的深度学习框架 (ML-DIP) 从低样本数据中重建3D实时心血管磁共振 (CMR). 这种方法可以实现高图像质量和准确的功能测量,而不需要完全采样的训练数据集.
科学领域:
- 医疗成像医学成像
- 心血管成像 - 心血管成像
- 人工智能在医学中的应用
背景情况:
- 实时3D心血管磁共振 (CMR) 成像对于评估心脏功能至关重要.
- 获取高分辨率的3DCMR数据通常需要很长的扫描时间,这限制了其临床实用性.
- 现有的重建方法通常依赖于完全采样的训练数据集,这些数据集并不总是可用.
研究的目的:
- 为3D实时CMR开发一个新的重建框架.
- 为了从高度低采样的k空间数据中实现高质量的图像重建.
- 在重建过程中消除对完全采样训练数据集的需求.
主要方法:
- 开发了一个多动态低级深度图像预先 (ML-DIP) 框架.
- 利用单独的神经网络来建模空间图像内容和变形场.
- 每次扫描优化网络,直接从低采样的k空间数据重建动态图像系列.
主要成果:
- 在幻影研究中,ML-DIP实现了高峰信号噪声比 (PSNR > 29 dB) 和结构相似度指数 (SSIM > 0.90),扫描时间短至两分钟.
- 在体内研究表明,功能测量与2D cine相比,图像质量优于基于5D-Cine的5D-Cine,即使在运动期间.
- 该框架成功地重建了早发性心室收缩 (PVC) 患者的不规则心跳,保持了节拍变化.
结论:
- ML-DIP可实现高质量的3D实时CMR重建,具有显著的加速度因子.
- 该框架直接从低样本数据中学习低级空间和运动表示.
- 这种方法克服了现有方法的局限性,因为不需要外部完全采样的培训数据集.
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