亚临床甲状腺功能低下症或亚临床甲状腺功能过强症患者的手握强度与euthyroid个体的手握强度相比:系统性审查和元分析
Ana M Fernández-Alonso1, Pascual García-Alfaro2, Faustino R Pérez-López3
1Department of Obstetrics and Gynecology, Torrecárdenas University Hospital, Almería, Spain.
Maturitas
|November 26, 2025
概括
亚临床甲状腺功能低下症患者的手握强度相比,甲状腺功能良好的人的手握强度降低. 在患有亚临床甲状腺功能障碍的人群中,没有观察到手握强度的显著差异.
科学领域:
- 内分泌学 在内分泌学.
- 肌肉骨健康 肌肉骨健康
- 公共卫生 公共卫生
背景情况:
- 亚临床甲状腺功能障碍,包括亚临床甲状腺功能障碍和亚临床甲状腺功能障碍,影响着人口的很大一部分.
- 手握强度是整体肌肉强度和功能能力的关键指标.
- 了解亚临床甲状腺功能障碍对肌肉力量的影响,对于早期干预和管理至关重要.
研究的目的:
- 系统地审查和对亚临床甲状腺功能低下症或亚临床甲状腺功能过强症患者手握强度的现有证据进行元分析.
- 为了比较这些患者群体的手握强度与无甲状腺患者的手握强度.
- 为了确定亚临床甲状腺功能障碍和肌肉力量缺陷之间的潜在关联.
主要方法:
- 在Web of Science,Scopus和PubMed进行了全面的文献搜索.
- 包括横截面研究,比较亚临床的甲状腺功能低下或甲状腺功能高的患者和euthyroid对照.
- 进行了随机效应元分析,使用纽卡斯尔-太华尺度评估研究质量.
主要成果:
- 亚临床的甲状腺功能低下症与手握强度显著降低 (SMD: -0.61) 和肉症风险增加 (OR: 2.12) 相比,甲状腺功能良好的人.
- 患有亚临床甲状腺功能低下症的患者也表现出更高的BMI和总胆固醇水平.
- 在亚临床甲状腺功能障碍症患者和euthyroid个体之间,没有发现手握强度的显著差异.
结论:
- 亚临床甲状腺功能低下与手握强度的降低和肉类的更高患病率有关.
- 亚临床甲状腺功能障碍似乎没有显著影响手握强度.
- 这些发现强调了评估亚临床甲状腺功能低下症患者肌肉强度的重要性.
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