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Updated: Jan 10, 2026

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
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Published on: July 25, 2013

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优化的蛋白质-水相互作用和扭曲精炼产生平衡的原子化蛋白质力场

Tien Minh Phan1, Priyesh Mohanty2, Jeetain Mittal3,4,5

  • 1Artie McFerrin Department of Chemical Engineering, Texas A&M University, College Station, TX, USA. tienminhphan@tamu.edu.

Nature communications
|November 26, 2025
PubMed
概括

两个新的分子动力学 (MD) 力场,珀 ff03w-sc和珀 ff99SBws-STQ,改善了蛋白质结构和动力学的模拟. 这些精细的力场准确地模拟了折叠的蛋白质和内在无序的多.

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