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Updated: Jan 10, 2026

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
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来自Mycobacterium tuberculosis的Ku的寡合化促进了DNA突触

Sayma Zahid1, Sonia Baconnais2, Henrietta Smith3

  • 1Leicester Institute for Structural and Chemical Biology, Department of Molecular and Cell Biology, University of Leicester, Leicester, UK.

Nature communications
|November 26, 2025
PubMed
概括

结核菌菌 Ku 蛋白质通过通过非同类末端连接修复DNA损伤,对生存至关重要. 结构研究揭示了它的DNA结合机制,这对细菌弹性和潜在的治疗点至关重要.

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