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Updated: Jan 10, 2026

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抗体通过连接体模拟和全oster干扰来破坏细菌粘附

Kelli L Hvorecny1, Gianluca Interlandi2, Tim S Veth3

  • 1Department of Biochemistry, University of Washington, Seattle, WA, USA.

Nature communications
|November 26, 2025
PubMed
概括

细菌粘附FimH使用异质过渡来进行宿主细胞的附着. 针对FimH的抗体采用了多种机制,包括连接体仿真和 conformational 稳定,提供新的抗菌策略.

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