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Updated: Jan 10, 2026

Oct4GiP Reporter Assay to Study Genes that Regulate Mouse Embryonic Stem Cell Maintenance and Self-renewal
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Oct4GiP Reporter Assay to Study Genes that Regulate Mouse Embryonic Stem Cell Maintenance and Self-renewal

Published on: May 30, 2012

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由Lin28b uORF编码的微蛋白PLUM是多能性和胚胎发育的细胞质决定因素

Zhihong Hao1,2,3,4, Yi Wu1, Yile Huang2

  • 1Institute of Development and Regeneration, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangdong-Hong Kong Joint Laboratory for Stem Cell and Regenerative Medicine, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, GIBH-HKU Guangdong-Hong Kong Stem Cell and Regenerative Medicine Research Centre, China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.

Nature communications
|November 26, 2025
PubMed
概括

一种新型的微蛋白质PLUM通过整合RNA代谢和线粒体活动来调节多能性. 它的耗尽加速了先天性状态的获得,影响了早期发育和胚胎植入.

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