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产后早期的微生物流入加强了眼睛表面,并防止小鼠的过敏眼病

Yanbo Liu1, Hang Sun2, Shulin Song1

  • 1Xiamen Eye Center and Eye Institute of Xiamen University, Fujian Provincial Key Laboratory of Ophthalmology and Visual Science, School of Medicine, Xiamen University, Xiamen, Fujian, China.

Communications biology
|November 26, 2025
PubMed
概括

结膜微生物组的早期定居对于眼睛表面平衡至关重要. 在小鼠中破坏这种微生物发育会增加对过敏眼病的易感性.

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Development of Immunocompetence01:22

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The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
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