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通过准细胞壁核组装蛋白CpsA,ACA可以杀死结核菌和M. bovis

Feng Huang1, Mengcong Shi1, Liu Chen1

  • 1National Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, China.

Communications biology
|November 26, 2025
PubMed
概括

一种新的化合物,3-azidothiophene-2-carboxylic acid (ACA),通过破坏其细胞壁组装,有效地杀死结核菌菌. ACA针对CpsA1和CpsA2酶,提供了对抗耐药结核病的潜在策略.

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