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Updated: Jan 10, 2026

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鼠T细胞受体OT-I表现出异物和自身抗原之间的不完善歧视

Anna Huhn1, Mikhail A Kutuzov1, Keir Maclean1

  • 1Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.

The EMBO journal
|November 26, 2025
PubMed
概括

T细胞使用T细胞受体 (TCRs) 来区分外来和自身抗原. 新的方法揭示了OT-I TCR显示不完美的,但增强的歧视,与动力校对模型保持一致.

关键词:
亲密关系 (Affinity) 是一种关系.抗原歧视的原因OT-I TCR 的时间表.表面等离子体共振是什么?一个T细胞细胞.

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