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Updated: Jan 10, 2026

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer
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Published on: July 28, 2010

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铁稳态和细胞克隆性驱动癌症相关的肠道DNA甲基化漂移在衰老中

Anna Krepelova1,2,3, Mahdi Rasa1,4, Francesco Annunziata1,5

  • 1Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), Jena, Germany.

Nature aging
|November 26, 2025
PubMed
概括

表观遗传漂移,衰老的标志,与癌症有关. 这项研究揭示了其起源于肠道干细胞,由炎症和Wnt信号驱动,为衰老和癌症表观遗传学提供了洞察力.

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