转录因子LF1通过与GmTCP3和GmLFY信号网络相互作用来控制复合叶的发育
Xuemei He1,2, Min Zhang1, Yanting Shen3
1Key Laboratory of Seed Innovation, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China.
Journal of integrative plant biology
|November 26, 2025
概括
大豆叶片数量的变化是由LF1基因控制的,这是一个AP2/ERF转录因子. LF1与GmTCP3和GmLFY相互作用,调节复合叶的发育和植物结构.
科学领域:
- 植物生物学 植物生物学
- 遗传学 是一个遗传学.
- 分子生物学分子生物学
背景情况:
- 叶子形态和复合叶子的发育对于植物结构至关重要,但在大豆中人们对其了解甚少.
- 豆类品种在叶片数量上表现出显著的差异,从三叶状结构到五叶状结构.
研究的目的:
- 为了确定控制大豆叶片数变化的遗传调节者.
- 阐明大豆复合叶子发育背后的分子机制.
主要方法:
- 基因映射用于识别关键基因.
- 在叶子组织中的基因表达分析.
- 转基因方法研究基因功能 (过度表达).
- 在CRISPR-Cas9基因编辑中.
- 蛋白相互作用测试. 蛋白相互作用测试.
- 对cis元素结合和基因诱导的分析.
主要成果:
- 鉴定出AP2/ERF转录因子LF1是传单号的关键调节者.
- LF1的表达局限于叶子启动部位,并直接影响叶片的发育.
- LF1表现出负的自我调节,并与GmTCP3.3相互作用.
- GmTCP3的CRISPR编辑影响了叶边缘和传单号码.
- LF1积极调节GmLFY的表达,这是一个已知的传单发育调节器.
结论:
- LF1是大豆叶片形态发生的中央调节者.
- LF1与GmTCP3和GmLFY的相互作用为复合叶发育的遗传控制提供了新的见解.
- 了解这些遗传通路可以为修改大豆植物结构的策略提供信息.
关键词:
在GWAS中,GWAS就是GWAS.LF1 一个LF1复合叶复合叶是一种复合叶.传单 宣传片 传单 宣传片豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆更多相关视频
11:04Geomagnetic Field Gmf and Plant Evolution: Investigating the Effects of Gmf Reversal on Arabidopsis thaliana Development and Gene Expression
Published on: November 30, 2015
13.9K
10:08Experimental Design for Laser Microdissection RNA-Seq: Lessons from an Analysis of Maize Leaf Development
Published on: March 5, 2017
10.0K
相关概念视频
Master Transcription Regulators
7.7K
Master transcription regulators are regulatory proteins that are predominantly responsible for regulating the expression of multiple genes. Often these genes work in concert to drive a complex process. Activation of a master transcription regulator can lead to a cascade of transcriptional activation necessary for that outcome. These regulators can directly bind to the regulatory sequences of the various genes involved, or they can indirectly regulate transcription by binding to regulatory...
7.7K
Master Transcription Regulators
2.7K
2.7K
General Transcription Factors
6.7K
Tissue-specific transcription factors contribute to diverse cellular functions in mammals. For example, the gene for beta globin, a major component of hemoglobin, is present in all cells of the body. However, it is only expressed in red blood cells because the transcription factors that can bind to the promoter sequences of the beta globin gene are only expressed in these cells. Tissue-specific transcription factors also ensure that mutations in these factors may impair only the function of...
6.7K
Combinatorial Gene Control
9.5K
Combinatorial gene control is the synergistic action of several transcriptional factors to regulate the expression of a single gene. The absence of one or more of these factors may lead to a significant difference in the level of gene expression or repression.
The expression of more than 30,000 genes is controlled by approximately 2000-3000 transcription factors. This is possible because a single transcription factor can recognize more than one regulatory sequence. The specificity in gene...
The expression of more than 30,000 genes is controlled by approximately 2000-3000 transcription factors. This is possible because a single transcription factor can recognize more than one regulatory sequence. The specificity in gene...
9.5K
Transcription Factors
82.2K
Tissue-specific transcription factors contribute to diverse cellular functions in mammals. For example, the gene for beta globin, a major component of hemoglobin, is present in all cells of the body. However, it is only expressed in red blood cells because the transcription factors that can bind to the promoter sequences of the beta globin gene are only expressed in these cells. Tissue-specific transcription factors also ensure that mutations in these factors may impair only the function of...
82.2K
TGF - β Signaling Pathway
10.4K
The TGF-β signaling pathway regulates cell growth, differentiation, adhesion, motility, and development. TGF-β ligands that induce TGF-β signaling are synthesized in their latent form. Several proteases or cell surface receptors such as integrins act upon the latent form, releasing the active ligand. There are three types of mammalian TGF-βs: (TGF-β1, TGF-β2, and TGF-β3) that bind as homodimers or heterodimers to TGF-β receptors. The TGF-β receptors...
10.4K
