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在乳腺瘤球状体中,β-lapachone 损害了活力,迁移和上皮-介质细胞过渡

Laura Lacerda Coelho1,2, Matheus Menezes Vianna1,2, Debora Moraes da Silva1,2

  • 1Laboratory of Innovations in Therapies, Education and Bioproducts, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil.

BMC cancer
|November 27, 2025
PubMed
概括

自然化合物β-lapachone (β-lap) 显示出作为乳腺癌的抗癌药物具有前途. 它有效地减少了瘤球形尺寸,并抑制了3D培养中的细胞活力和迁移.

关键词:
乳腺癌 乳腺癌 乳腺癌皮质 - 介质细胞过渡.三维细胞培养培养的三维细胞培养贝塔拉帕是一种β-lapachone.

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