神经成像对跨性别和性别非确认青年的洞察:一个范围审查
Linda M Bonnekoh1,2, Angela Rölver3, Ida Wessing3
1Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Münster, Schmeddingstraße 50, 48149, Münster, Germany. lindameredith.bonnekoh@ukmuenster.de.
Child and adolescent psychiatry and mental health
|November 27, 2025
概括
关于青少年性别不一致 (GI) 的研究表明,纵向神经成像研究显著缺乏. 未来的研究必须包括非二进制个体和伦理考虑,以便对性别认同有细微的理解.
科学领域:
- 神经科学是一个神经科学.
- 青少年医学 青少年医学
- 精神病学是一个精神病学.
背景情况:
- 性别不一致 (GI) 涉及分配的性别和性别认同之间的不匹配,导致痛苦.
- 建议GI的生物学基础,但青少年的神经生物学相关性不明.
- 目前关于GI/GD青少年脑成像的研究是有限的.
研究的目的:
- 审查目前的青少年 (22岁以下) 性别失调/GI的MRI脑部发现.
- 在审查中包括非二进制识别青少年.
- 讨论研究结果,考虑样本特征,荷尔蒙疗法和伦理含义.
主要方法:
- 使用关键词的PubMed/Medline系统审查:性别失调,性别不一致,性别认同,非二进制,MRI,青少年.
- 包括ICD-11术语更改之前发表的文献,使用"跨性别主义".
- 预先注册的协议 (INPLASY2023110074). 这是一份备忘录.
主要成果:
- 从360篇扫描文章中,包括了20项研究.
- 大多数研究都专注于功能成像,并使用横截面设计.
- 只有3个纵向研究存在女性对男性个体的性别肯定激素治疗 (GAHT);没有男性对女性.
- 非二进制的方面和道德方面的影响很少被解决.
结论:
- 对于GI/GD的青少年,缺乏强大的神经影像数据,特别是纵向研究.
- 非二进制青少年需要更多的研究纳入.
- 未来的研究应该整合非二进制个体和伦理考虑,以避免污名化,并促进对性别认同的细微理解.
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