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Updated: Jan 10, 2026

Author Spotlight: Decoding Mitochondrial Aging
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CISD2确保了足够的ER-线粒体合,关键支持神经元中的线粒体功能

Jens Loncke1, Ian de Ridder1, Rita La Rovere1

  • 1Laboratory for Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine, KU Leuven, Campus Gasthuisberg O/N-1 B-802, Herestraat 49, 3000, Leuven, Belgium.

Acta neuropathologica communications
|November 27, 2025
PubMed
概括

失去Cisd2蛋白质会损害细胞区间间的 (Ca2+) 转移,特别是影响沃尔夫拉姆综合征2型 (WS2) 中的神经元功能和弹性. 这突出了Cisd2的作用.

关键词:
细胞灭亡 (apoptosis) 是一种死亡的过程.在Ca2+信号传输中.这就是Cisd2的意思.在ER-线粒体的接触点.神经退行发生神经退行.沃尔夫拉姆综合征是什么意思

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