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Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis
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叶酸通过PI3K/AKT/NF-κB/MLCK轴的抑制减轻性结肠炎,恢复肠壁的完整性

Shize Zhang1, Tian Cheng1, Yuang Chen1

  • 1Jiangsu Provincial Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.

Biology
|November 27, 2025
PubMed
概括

叶酸作为抗性结肠炎 (UC) 的保护因素. 在大肠炎模型中补充叶酸可以减少疾病的严重程度,并通过向特定的分子通路恢复肠道屏障功能.

关键词:
在PI3K/AKT/NF-κB/MLCK/MLC2轴上叶酸是什么 叶酸是什么 叶酸是什么肠道屏障 肠道屏障 肠道屏障门德尔的随机化是门德尔的随机化性结肠炎是一种

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