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Updated: Jan 10, 2026

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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cGAS-STING-NF-κB轴通过线粒体DNA释放调解轮激素诱导的NLRP3炎症酶激活

Yewon Mun1, Juseo Kim1, You-Jin Choi2

  • 1College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Republic of Korea.

Antioxidants (Basel, Switzerland)
|November 27, 2025
PubMed
概括

轮通过激活cGAS-STING通路引发炎症,从而导致NLRP3炎症酶激活. 这种线粒体功能障碍途径涉及活性氧物种和线粒体DNA释放,促进细胞信号传递.

关键词:
在 NF-κBB 中.在NLRP3炎症酶体中,NLRP3炎症cGASSTING通道的路径线粒体DNA是线粒体DNA的组成部分.轮回一个,一个.

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