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运动成和COL1A1基因rs1800012多态对精英女排球员受伤易感性的影响
Muhammed Mustafa Piri1, Mesut Cerit1, Murat Anılır2
1Department of Exercise and Sports Science, Lokman Hekim University, 06510 Ankara, Türkiye.
Genes
|November 27, 2025
概括
运动成的精英女排球员和原体I型α1链 (COL1A1) rs1800012 T等位基因面临着更高的受伤风险. 此外,T等位基因还与受伤后更长的恢复时间相关.
科学领域:
- 运动医学 运动医学
- 遗传学 遗传学 是一个
- 心理学 心理学 心理学
背景情况:
- 精英女排球员容易受伤害.
- 遗传因素,如COL1A1 rs1800012多态,可能会影响受伤风险.
- 运动成是导致运动伤害的潜在因素.
研究的目的:
- 调查运动成和COL1A1rs1800012 G/T多态性对精英女排球员受伤易感性的独立影响.
- 为了确定COL1A1 T等位基因是否在排球运动员中比一般人群少.
主要方法:
- 一项涉及50名土耳其女排球员和557名土耳其对照,以及53名俄罗斯女排球员和810名俄罗斯对照的病例对照研究.
- 包括对土耳其参与者的运动成评估和受伤数据.
- 对于COL1A1 rs1800012 G/T多态的基因造型.
主要成果:
- 受伤的球员在运动成量表的个人社会需求延迟和冲突分量表上获得更高的分数 (p=0.036).
- 与对照组相比,排球运动员中观察到COL1A1 T等位基因的频率明显较低 (合并OR=0.63,p=0.031).
- 与GG基因型 (28.0%,p=0.017) 相比,GT基因型与受伤运动员 (57.1%) 的恢复时间长 (≥3个月) 相关.
结论:
- 运动成和COL1A1 rs1800012 T等位基因与精英女排运动员受伤率的增加有关.
- COL1A1 T等位基因与受伤后长时间恢复的风险较高有关.
- 这些发现突出了精英运动员心理因素,遗传倾向和受伤结果之间的相互作用.
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