基于深度学习的腿部自动肌肉细分,使用下肢CT图像
Young Jae Kim1, Ji-Eun Kim2, Yeonho Park3
1Gachon Biomedical & Convergence Institute, Gachon University Gil Medical Center, Incheon 21565, Republic of Korea.
Diagnostics (Basel, Switzerland)
|November 27, 2025
概括
深度学习精确地从CT扫描中对大腿肌肉进行细分,有助于肉症和代谢研究. 这种自动化方法为肌肉骨研究提供了可靠的定量肌肉分析.
科学领域:
- 肌肉骨研究的研究.
- 代谢研究的研究.
- 医学成像分析分析 医学成像分析
背景情况:
- 肉症和肌肉组成是肌肉骨和代谢研究的关键指标.
- 准确的定量肌肉评估对于理解这些疾病至关重要.
研究的目的:
- 开发和验证使用非对比CT图像进行大腿肌肉细分的自动深度学习方法.
- 量化评估大腿肌肉,包括瘦身和脂肪体积.
主要方法:
- 实施了三种深度学习模型 (Dense U-Net,MANet,SegFormer),并对大腿肌肉细分进行了比较.
- 模型在136次CT扫描中接受了训练,并在40次外部扫描中得到了验证.
- 细分性能被评估使用子相似系数 (DSC),灵敏度,特异性和准确性.
主要成果:
- 所有模型都实现了高细分精度 (平均DSC>96%).
- 在内部验证中,MANet表现出色;在外部验证中,SegFormer表现出卓越的体积一致性 (ICC ≥0.995,p<0.01).
- 自动化定量指数与人工测量非常接近.
结论:
- 一个深度学习框架可以从CT扫描中准确,可重现的细分功能大腿肌群.
- 对比分析支持基于CT的定量肌肉评估对萨尔科佩尼亚和肌肉骨研究的可行性.
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