在剖腹产中进行局部麻醉时评估血液动力学变化:USCOM®的作用
Agnese Lambertini1, Sara Doroldi2, Stefania Maria Mucci1
1General and Pediatric Anesthesia and Intensive Care Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Diagnostics (Basel, Switzerland)
|November 27, 2025
概括
剖腹产的局部麻醉可以导致低血压. 使用USCOM的基线血液动力学监测可以预测血管压缩剂的需求并影响新生儿的结果,从而允许个性化护理.
科学领域:
- 麻醉学 麻醉学
- 产科 产科 产科 产科 产科
- 心血管生理学心血管生理学
背景情况:
- 局部麻醉 (LRA) 通常用于剖腹产 (CS),但往往导致低血压.
- 在CS期间的低血压可能会对母亲的血液动力学和胎儿的健康产生负面影响.
- 预测和管理这些血液动力学变化对于患者的安全至关重要.
研究的目的:
- 确定基线血液动力学特征是否预测CS期间LRA后的变化.
- 确定血管压缩剂需求和新生儿不良结果的预测因素.
- 评估非侵入性心脏输出监测在CS中的实用性.
主要方法:
- 一项前性观察性研究,涉及与LRA进行选择性CS的女性.
- 使用USCOM®监测血液动力学参数 (心脏输出,中风体积,全身血管阻力).
- 使用多级线性回归分析,将基线血液动力学与血管压缩剂使用和新生儿结局相关联.
主要成果:
- LRA显著降低了血压和心率.
- 较低的基线中风体积指数 (SVI) 与增加的血管压缩剂需求有关 (p=0.050).
- 较低的基线心电输出 (CO) 和心脏指数 (CI) 与新生儿pH值降低相关,CI与pH值<7.20 (p=0.043) 有关.
结论:
- 在CS期间,USCOM®提供实时,非侵入性的血液动力学数据.
- 基线SVI,CO和CI是LRA后并发症的有价值预测因素.
- 在CS期间个性化血液动力学管理可以通过持续监测来加强.
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