乳腺癌诊断和治疗的延迟:区域差异
Daniel Augusto Nunes de Lima1, Fernando Castilho Pelloso2, Elton da Cruz Alves Pereira1
1Program in Health Sciences, State University of Maringá, Maringá 87020-900, Paraná, Brazil.
Cancers
|November 27, 2025
概括
乳腺癌治疗的延迟,特别是放射治疗和手术,加剧了巴西患者的治疗结果. 这些延迟不成比例地影响了人力发展指数 (HDI) 较低的地区,突出了公平的医疗保健政策的需要.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 健康差异 在健康上的差异
背景情况:
- 乳腺癌是全球女性癌症死亡的主要原因之一.
- 巴西在乳腺癌诊断和治疗方面面临着显著的区域差异.
- 人类发展指数 (HDI) 较低的地区由于这些差异而经历了更糟糕的临床结果.
研究的目的:
- 评估延迟开始乳腺癌治疗与临床结果之间的关联.
- 分析治疗延迟的区域差异及其在巴西的影响.
- 确定人类发展指数 (HDI) 对治疗及时性和结果的影响.
主要方法:
- 使用来自DATASUS (2013-2023) 的二次数据进行的观察性研究.
- 对治疗类型 (手术,化疗,放射治疗) 和延迟间隔 (≤30,31-60,>60天) 的分析.
- 使用皮尔森相关性和线性回归的统计分析,按HDI分层.
主要成果:
- 延迟超过60天与较差的乳腺癌结局相关.
- 放射治疗与结果有显著的负相关性 (r = -0.6624).
- 人类发展指数较低的地区 (北方,东北) 延迟时间较长,延迟与死亡率之间的联系较强.
结论:
- 延迟治疗,特别是放射治疗和手术,会对巴西的乳腺癌存活率产生负面影响.
- 治疗延迟的不良影响在较低的HDI地区更为严重.
- 有针对性的区域公共卫生政策对于减少差距和改善乳腺癌结果至关重要.
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