什么时候和对谁来说,重症监护室的入院会改变瘤学的预后吗? - - 一个全面的审查
Ioana Roxana Codru1,2, Liliana Vecerzan1,3
1Faculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania.
Cancers
|November 27, 2025
概括
癌症患者入住重症监护室 (ICU) 可以成为治疗桥梁,但好处仅限于可逆状况和可信的癌症控制. 徒劳性与器官支持负担和耐火性疾病有关.
科学领域:
- 关键护理医学 关键护理医学
- 在瘤学瘤学.
- 证据综合 证据综合
背景情况:
- 在瘤学中,重症监护室 (ICU) 的作用已经从终身护理演变为癌症治疗的潜在桥梁.
- 缺乏明确的标准来区分有益的ICU干预与癌症患者的徒劳护理.
研究的目的:
- 审查当代证据 (2015-2025年) 关于成年癌症患者入院ICU的结果.
- 在癌症患者的ICU入院后,确定与改善预后相关的临床因素.
主要方法:
- 使用PCC框架进行了PRISMA-ScR范围审查.
- 在PubMed中从2015-2025年进行了搜索,采用双重选和数据提取.
- 在6个定义的癌症患者护理集群中应用了叙事和主题综合.
主要成果:
- 七十三项研究 (>170,000人) 显示加权平均ICU死亡率约为41%,一年死亡率为62%.
- 在早期入院,单个器官衰竭,缓解,术后监测和可逆毒性 (例如ICI肺炎,CAR-T CRS/ICANS) 中观察到益处.
- 徒劳性与多器官支,延长RRT,耐火性疾病和表现不佳状态 (ECOG ≥3) 有关.
结论:
- 当急性侮辱是可逆的,癌症控制是可行的时,ICU护理可以改变癌症患者的预后.
- 高的器官支负担和耐火性癌症疾病表明实际的徒劳值.
- 研究结果支持时间有限的ICU试验,败血症/免疫相关不良事件的早期干预,以及综合性息治疗.
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