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角膜折射参数的年龄相关趋势:对健康眼睛视频角质谱的里埃分析

Shumei Tan¹, Ziyuan Liu¹, Yuanting Li¹

¹Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Department of Ophthalmology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing 100191, China.

|November 27, 2025

概括

这项研究分析了健康眼睛的角膜折射功率参数如何随着年龄的增长而变化. 研究结果揭示了与年龄相关的明显趋势,以及临床应用至关重要的最小球形折射功率和形的拐点.

科学领域:

眼科医生眼科眼科
眼镜测量是指眼睛的测量.
生物医学工程生物医学工程

背景情况:

角质参数对于折射误差评估至关重要.
了解健康角膜与年龄相关的变化对于临床诊断和手术规划至关重要.
里埃转换分析提供了详细的角膜折射功率数据.

研究的目的:

在没有角膜疾病的个体中调查角膜折射参数的分布和与年龄相关的趋势.
为了分析最小的球形折射功率 (SphRMin),中央正规白 (Asti.Central),外围正规白 (Asti.Periph) 和不规则白 (Irregul).
为了确定这些角膜参数中的与年龄相关的变化和拐点.

主要方法:

对2545名年龄在4-95岁之间,没有角膜疾病的患者 (5074只眼睛) 进行了回顾性横截面研究.
分析了源自富里埃转换的角质折射功率参数.
统计分析比较了各年龄组的参数,并使用线性和非线性方程建模了与年龄相关的变化.

主要成果:

对于健康队列,SphRMin,Asti.Central,Asti.Periph和Irregul的平均值被确定.
在不同年龄组中观察到Asti.Central,Asti.Periph和Irregul的显著差异 (p < 0.001).
所有分析的参数 (SphRMin,Asti.Central,Asti.Periph,Irregul) 与年龄有显著的相关性 (p < 0.001),为每个参数的趋势确定了特定的拐点.

结论:

该研究为角膜折射参数提供了从不同年龄段的健康人群中从富里埃转换获得的规范值.
确定了与年龄相关的趋势和SphRMin,Asti.Central,Asti.Periph和Irregul的关键转折点.
这些发现对诊断异常折射状况和指导眼科手术设计具有重大临床意义.

关键词:

富里埃数列分析富里埃数列分析角膜角膜角膜是一个不规则的纹不规则.常规的纹斑是什么意思

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