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相关概念视频

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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
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Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
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相关实验视频

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Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse
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无对比辐射的NIR肺部成像,没有对比辐射.

Jiří Votruba1, Martin Drahanský2, Tomáš Goldmann3

  • 1I. Clinic of Tuberculosis and Respiratory Diseases, General University Hospital in Prague, 128 08 Prague, Czech Republic.

Biomedicines
|November 27, 2025
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概括
此摘要是机器生成的。

这项研究引入了一种新的,无辐射的光学技术,使用近红外 (NIR) 透光来定位单独的肺结节 (SPN). 这种方法可视化肺组织,潜在地改善了没有X射线的活检指导.

关键词:
支气管镜检查 (bronchoscopy) 是一种支气管镜检查.图像处理是图像处理的过程.接近红外成像的近红外成像.胸腔镜检查 胸腔镜检查 胸腔镜检查单独的肺结节.转光是通过光照.

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科学领域:

  • 肺部医学 肺部医学
  • 医疗成像医学成像
  • 光学物理学 光学物理学

背景情况:

  • 孤独肺结节 (SPN) 的定位很困难,通常需要电离辐射.
  • 目前用于SPN检测的内镜导航方法面临限制.
  • 肺部手术需要使用非电离成像技术.

研究的目的:

  • 开发和评估一种新的,无辐射的光学方法,用于SPN定位.
  • 为了利用近红外 (NIR) 透光可视化肺膜.
  • 评估NIR透光用于胸内可视化的可行性.

主要方法:

  • 在支气管树中插入了一个小型的NIR光源.
  • 从胸腔侧检测到传输和散射的NIR光线,使用迷你胸腔镜和CMOS摄像头.
  • 该技术利用肺组织的内在光学特性,避免使用对比剂.

主要成果:

  • 通过直至4厘米的ex vivo猪肺膜体,清晰可视化组织结构.
  • 在一个通风的猪中,从腔中持续检测出支气管NIR照明.
  • 实现了分明的叶片结构和支气管粘膜的成像.

结论:

  • 近红外 (NIR) 透光提供无辐射的胸内可视化.
  • 这种技术显示出作为肺部手术中的活检指导辅助的前景.
  • 为了临床验证和转化为人类应用,需要进一步的研究.