阶段角度与血液透析患者的身体组成的关联:一个病例对照研究
Selma Cvijetić Avdagić1, Petra Kovačević Totić2, Karla Kovačević Čorak3
1Institute for Medical Research and Occupational Health, 10 000 Zagreb, Croatia.
Life (Basel, Switzerland)
|November 27, 2025
概括
组织完整性的标志物相角 (PhA) 在血液透析 (HD) 患者中较低. 在HD患者中,PhA反映了身体组成的变化,包括骨肌肉质量和骨质量.
科学领域:
- 生物医学科学 生物医学科学
- 临床营养学 临床营养学
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 接受血液透析 (HD) 的患者经常由于代谢障碍而表现出身体成分的改变.
- 阶段角 (PhA) 作为细胞完整性和整体生理状态的指标.
研究的目的:
- 评估身体组成及其与HD患者PhA的相关性.
- 为了比较HD患者和健康对照者之间的身体组成和PhA.
主要方法:
- 生物电阻分析 (BIA) 用于评估身体组成参数,包括骨肌肉质量 (SMM),脂肪组织和总骨质量 (BM).
- 阶段角 (PhA) 测量了53名HD患者和106名年龄和性别匹配的健康对照.
主要成果:
- 与对照组相比,HD患者的脂肪质量和PhA显著降低 (p < 0.001).
- 虽然在统计学上不显著,但在HD患者中,低SMM和BM的患病率更高.
- 在HD患者中,PhA在调整年龄和性别后与SMM% (p = 0.021) 和BM (p = 0.035) 有积极关联.
结论:
- 在HD患者和健康个体之间,PhA和身体组成之间的关系不同.
- 阶段角可以作为一种有价值的指标,用于检测血液透析患者的身体组成异常.
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