了解性的进展:一个神经肌肉骨建模的视角
Mohammad S Shourijeh1, Argyrios Stampas1, Shuo-Hsiu Chang1
1Department of Physical Medicine and Rehabilitation, UTHealth Houston McGovern Medical School, Houston, TX 77030, USA.
Journal of clinical medicine
|November 27, 2025
概括
神经肌肉骨 (NMS) 建模通过整合生物力学和神经动力学来提供客观的性评估. 这篇评论探讨了先进的NMS建模技术,用于在脑和中风等疾病中进行个性化治疗.
科学领域:
- 生物医学工程 生物医学工程
- 神经科学是一个神经科学.
- 康复科学 康复科学 康复科学
背景情况:
- 由于上部运动神经元病变导致的性,由于其复杂的神经和机械组成部分, presents诊断挑战.
- 目前的评估工具,如修改的Ashworth和Tardieu尺度,提供有限的,主观的洞察力的动态性质.
- 神经肌肉骨 (NMS) 建模通过整合生物机械和反射性质提供了定量,客观的方法.
研究的目的:
- 对NMS建模用于性评估的进步进行范围审查.
- 为了比较不同的建模方法 (机械,神经,综合) 和它们的临床应用.
- 确定将NMS建模转化为临床实践的障碍和未来方向.
主要方法:
- 系统的文献搜索关于NMS对性的建模研究.
- 基于机械,神经或综合方法的模型分类.
- 分析神经疾病 (如脑,中风) 中的模型应用.
主要成果:
- NMS建模提供了客观的定量数据,超越了传统的尺度.
- 结合生物力学和神经动力学的综合模型显示出全面评估的前景.
- 在脑和中风中证明了应用,突出了个性化治疗的潜力.
结论:
- 对于客观的性评估和个性化的治疗策略来说,NMS建模代表了重大进步.
- 克服计算和监管障碍对于临床采用至关重要.
- 未来的研究应该专注于实时模拟和机器学习集成,以提高临床实用性.
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