使用主动站立静态压力测试来评估长期COVID患者的生理反应:系统性审查
Faith Olarinde1, Albená Nunes-Silva2, Diana C Sanchez-Ramirez3
1Cardiorespiratory & Physiology of Exercise Research Laboratory, Faculty of Kinesiology and Recreation Management, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
Journal of clinical medicine
|November 27, 2025
概括
长期COVID (LC) 患者在活动站立测试期间表现出自主功能受损和心率升高. 这表明潜在的心血管和自主功能障碍有助于LC症状.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 生理学 生理学 生理学
背景情况:
- 长期COVID (LC) 经常与静态不耐症有关.
- 自主和心血管功能障碍是LC症状潜在的潜在机制.
- 活动站立测试是评估静态应激反应的宝贵工具.
研究的目的:
- 系统地审查活动站立静态应力测试的实用性.
- 评估患有LC的个体的心血管,自主和呼吸反应.
- 为了确定与LC相关的功能障碍相关的生理标志物.
主要方法:
- 系统的文献搜索 (PubMed,MEDLINE,EMBASE,CINAHL,Scopus,2020-2025年). 这是一个很好的方法.
- 包括使用活跃站立测试在LC和健康对照的成年人中的研究.
- 需要持续的节拍测量和生理结果报告.
主要成果:
- 三项研究 (216名LC参与者,186名对照) 符合标准.
- LC个体表现出持续升高的心率 (仰卧和站立).
- 血压反应各不相同;一些LC患者符合正静性低血压标准,另一些患者表现出腹压增加. 在LC组中观察到心率变化减少.
结论:
- 慢性心脏病与心率升高和活动站立时自主功能受损有关.
- 观察到的生理变化可能解释LC症状,如头和疲劳.
- 活动站立测试可以帮助识别自主功能障碍,并指导LC患者的康复.
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