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在功能性消化不良症患者治疗诱导后的长期结果
Takayuki Kitano1, Toshihiko Tomita1, Masatoshi Mieno1
1Department of Gastroenterology, Faculty of Medicine, Hyogo Medical University, Nishinomiya 663-8501, Hyogo, Japan.
Journal of clinical medicine
|November 27, 2025
概括
功能性消化不良 (FD) 通常需要长期治疗. 基线抑郁症和腹痛预测结果不佳,突出了对功能性消化不良患者综合心理和医疗管理的需要.
科学领域:
- 胃肠病学 胃肠病学
- 精神病学是一个精神病学.
背景情况:
- 功能性消化不良 (FD) 是一种常见的胃肠道疾病.
- 长期结果和FD的治疗耐药性因素需要进一步调查.
研究的目的:
- 评估FD在3年的长期成果.
- 确定与FD治疗耐药性相关的因素.
主要方法:
- 通过罗马四号标准诊断的111名FD患者的回顾性分析.
- 评估胃肠道症状 (GSRS),心理困扰 (HADS) 和生活质量 (SF-8).
- 用各种治疗方法评估1年和3年的治疗反应.
主要成果:
- 一年后症状改善率为50.5%,三年后改善率为80.2%.
- 较高的基线HADS-抑郁症和GSRS-腹痛得分预测了治疗耐药性.
- HADS-抑郁症和GSRS-腹痛是不良长期结果的独立预测因素.
结论:
- 飞行器疾病管理需要长期的治疗策略.
- 早期心理评估和综合护理对于改善FD结果至关重要.
- 在基线时抑郁症状和腹部疼痛是FD治疗耐药性的关键指标.
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