DDX23 5' UTR LNA-

Polina Kamzeeva1, Nikita Shepelev1,2, Veronika Zabbarova2

  • 1Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, The Russian Academy of Sciences, 117437 Moscow, Russia.

概括

研究人员探索了DDX23mRNA中的RNA结构,发现针头,而不是G-四重复合体,调节翻译. 针对这种针头的反感性寡核酸有效抑制了翻译,提供了新的抗癌治疗策略.

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