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Anti-virulent Disruption of Pathogenic Biofilms using Engineered Quorum-quenching Lactonases
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基于细菌的生物控制剂通过生物降解性抗菌剂杀死病原体,这些抗菌剂来自麦克罗拉克家族

Elena B Guglya1, Olga A Belozerova1, Anton E Shikov2,3

  • 1Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, 117997 Moscow, Russia.

International journal of molecular sciences
|November 27, 2025
PubMed
概括

百日菌 velezensis K-3618 产生巨乳素,强大的抗微生物药物对抗耐药细菌. 乙基化麦克罗拉克丁表现出增强的活性,但病原体降解降低了疗效,凸显了需要稳定的合成类似物.

关键词:
这种病原体是Bacillus velezensis.活动导向的代谢学.抗生素耐药性 抗生素耐药性生物控制剂 生物控制剂生物转化是一种生物转化.麦克罗拉克提因是什么?

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