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身体构成和代谢健康的年龄相关变化:成年人的横截面研究
Inga Fomčenko1, Inga Bikulčienė2, Dovilė Karčiauskaitė2
1Faculty of Medicine, Vilnius University, 01513 Vilnius, Lithuania.
40岁以后,代谢健康和身体成分发生显著变化,特别是在女性中,脂肪质量增加和不良的脂质概况. 这种中年过渡突出了代谢生物标志物和脂肪酸组成的明显的年龄和性别相关转变.
科学领域:
- 代谢健康 代谢健康
- 人体生理学 人体生理学
- 营养科学 营养科学
背景情况:
- 中年是代谢风险因素出现的关键时期.
- 了解代谢健康的年龄和性别相关变化对于预防策略至关重要.
研究的目的:
- 调查中年期脂质样本,身体组成,氧化应激和脂肪酸含量的与年龄和性别相关的变化.
- 为了确定40-49岁年龄组中发生的特定代谢变化,与年轻的成年人相比.
主要方法:
- 一项涉及169名成年人 (<30,30-39,40-49岁) 的横截面研究.
- 评估身体组成 (脂肪量,分布,瘦身量),禁食脂质,炎症标志物和血小板脂肪酸.
- 统计分析以比较跨年龄和性别群体的代谢概况.
主要成果:
- 与年轻人相比,年龄在40-49岁的成年人表现出更高的脂肪质量,特别是在女性中,并且总体上更糟糕的代谢特征 (较高的总胆固醇,LDL,甘油三,葡萄糖).
- 在40-49组与30-39组相比,观察到麦隆迪甲 (氧化应激标志物) 的增加.
- 40-49岁的女性表现出更不利的脂质和血糖特征;这个群体的血小板脂肪酸显示出更高的多不和脂肪酸和omega-6百分比,包括特定脂肪酸,如酸和酸.
结论:
- 40岁以后,身体组成,代谢生物标志物和血小板脂肪酸概况出现了与年龄相关的显著变化,具有显著的性别特异性差异.
- 生命的第五个十年代表了一个过渡阶段,其特点是中心脂肪增加,代谢健康下降和脂肪酸成分变化,特别是在女性中.
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