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Updated: Jan 10, 2026

Molecular Modulation by Lentivirus-Delivered Specific shRNAs in Endoplasmic Reticulum Stressed Neurons
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EIF2α-PERK信号通路通过内质网膜应激介导暴露诱导的A1型天体细胞激活,通过内质网膜应激激活

Jing Wang1, Tingting Guo1, Yang Hu1

  • 1Department of Occupational & Environmental Health, The Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Fourth Military Medical University, Xi'an 710032, China.

Toxics
|November 27, 2025
PubMed
概括

(Mn) 暴露会通过激活星球细胞和ER应激引起神经毒性. 抑制PERK通路可以减少这种损伤,减轻运动缺陷,并为毒性提供潜在的治疗策略.

关键词:
一个叫Perk的Perk.星球细胞是星球细胞.酸是一种酸.线粒体中的线粒体.神经炎症是一种神经炎症.

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