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Updated: Jan 10, 2026

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向基因型告知剂量沃里可纳:使用人口药动力学模型对整个CYP2C19表型进行头对头模拟

Yeobin Lee1, Nai Lee1, Su-Jin Rhee2

  • 1College of Pharmacy, Daegu Catholic University, Gyeongsan 38430, Republic of Korea.

Pharmaceutics
|November 27, 2025
PubMed
概括

选择正确的群体药理动力学 (PopPK) 模型对于指导伏利可纳剂量至关重要. 不同的模型影响预测的药物暴露,影响治疗药物监测 (TDM) 和基于其CYP2C19基因型的患者的初始剂量选择.

关键词:
在CYP2C19中.基于模型的精确剂量定量.人口的药理动力学治疗药物监测 治疗药物监测沃里康纳 (Voriconazole) 是一种一种

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