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Updated: Apr 12, 2026

Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes
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超分子脂质纳米颗粒基于氨基β-CD宿主-客脂质:设计,机制和生物安全性

Pin Lv1,2,3, Yamin Li1, Gang Du1

  • 1Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.

Pharmaceutics
|November 27, 2025
PubMed
概括

研究人员开发了使用宿主-客化学来简化LNP构造的新型超分子脂质纳米粒子 (LNP). 这些功能性脂质纳米颗粒显示出高效的药物输送和向性脏积累,为脏疾病治疗提供了潜力.

关键词:
酸性 响应pH的酸性药物输送是药物输送的过程.配方研究研究 配方研究针对脏的目标多个阶段的组装组合.

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After oral administration, poor permeability often limits the rate at which drugs are absorbed through the intestinal epithelium. Enhancing drug permeability is crucial for effective therapy, and several strategies have been developed to overcome this challenge.One effective strategy involves the use of lipid-based formulations. These formulations enhance dissolution and solubility, targeting physiological mechanisms to increase drug absorption. This includes stimulating bile salt secretion,...
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