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Updated: Jan 10, 2026

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一个多晶2A设计是否能够为抗体药理动力学研究提供功能性FcRn生产?

Valentina S Nesmeyanova1, Nikita D Ushkalenko1, Sergei E Olkin1

  • 1State Scientific Center of Virology and Biotechnology "Vector", Rospotrebnadzor, 630559 Koltsovo, Novosibirsk Region, Russia.

Pharmaceutics
|November 27, 2025
PubMed
概括

研究人员开发了一种新的多基斯特龙结构,用于高效地产生功能性新生儿Fc受体 (FcRn). 这一突破促进了具有改善药理动力学特性的工程抗体的查.

关键词:
2A类的类.新生儿的Fc受体.这是一种pH值依赖的结合.这种表达方式是多基斯特龙式表达.

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