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不同表面活性剂对帕克利塔克塞尔/HPMC-AS无形固体分散剂口服生物可用性的影响

Chenzhao Zhang1, Siyi Mao1, Jinhua Yuan1

  • 1School of Pharmacy, Minzu University of China, Beijing 100081, China.

Pharmaceutics
|November 27, 2025
PubMed
概括

表面活性剂的选择显著影响无形固体分散 (ASD) 的性能. 兼容的表面活性剂通过改善溶解和保持无形稳定性来增强帕克利塔塞尔 (PTX) 的生物可用性,而不兼容的表面活性剂则会降低其.

关键词:
无形固体分散 (ASD) 的方法口服生物可用性 口服生物可用性帕克利塔塞尔 (PTX) 是一种药物.水溶性较差的药物药物.表面活性剂是一种表面活性剂.

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