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Updated: Jan 10, 2026

Experimental Infection with Listeria monocytogenes as a Model for Studying Host Interferon-γ Responses
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GLP-1类比的利拉格卢提德通过性别依赖的神经炎症调节来降低发烧

Gabriela L Soares de Sousa1, Ester K Martins da Cruz1, Sara C Rojas de Aguiar1

  • 1Laboratory of Experimental Biomodels, Faculty of Health Sciences and Technology, University of Brasília, Brasília 72220-275, DF, Brazil.

Pharmaceuticals (Basel, Switzerland)
|November 27, 2025
PubMed
概括

利拉格卢提德 (LIRA) 通过性别特定的途径降低了老鼠的发烧. 在男性中,它降低了前列腺素E2 (PGE2);在女性中,它降低了互白素-6 (IL-6) 并增加了血清素 (5-HT).

关键词:
这是一种抗发烧药.在下丘脑中,下丘脑互乐金-6是其中的一种.脂多糖类糖化物 (Lipopolysaccharide) 是一种多糖类糖.的前列腺素E2的前列腺素E2.血清胺 (serotonin) 是一种神经元.

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