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Updated: Jan 10, 2026

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α
11:27

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α

Published on: November 2, 2018

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建模完整的非活跃PKC-δ结构,以探索监管可访问性和选择性准机会

Rasha Khader1,2, Lodewijk V Dekker1

  • 1School of Pharmacy, Biodiscovery Institute, University of Nottingham, Nottingham NG7 2RD, UK.

Pharmaceuticals (Basel, Switzerland)
|November 27, 2025
PubMed
概括

全长非活性蛋白激酶C-δ (PKC-δ) 的结构建模确定了新的结合位点. 这项研究为开发针对癌症的向疗法提供了一个框架,通过使选择性PKC-δ调制成为可能.

关键词:
乳腺癌 乳腺癌 乳腺癌进行比较建模.激酶调节 激酶调节带对接对接器蛋白质激酶 C-δδ 的作用.

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