炎症性肠病儿童的超加工食品摄入量:试点病例控制研究
Emese Kasznár1,2, Dorina Bajzát1,2, Anna Karoliny1
1Heim Pál National Pediatric Institute, 1089 Budapest, Hungary.
Nutrients
|November 27, 2025
概括
患有炎症性肠病 (IBD) 的儿童比健康儿童消费的超加工食品 (UPF) 多. 这项试点研究发现,儿科性结肠炎患者的UPF摄入量较高,但克罗恩病患者的摄入量较高.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 营养科学 营养科学
- 炎症性肠病 (IBD) 研究研究
背景情况:
- 全球超加工食品 (UPF) 消费量上升,特别是在发达国家.
- UPF是能量密度高,营养不良,可能会对肠道健康和肠道透性产生负面影响.
- 加工食品,IBD发病,进展和治疗反应之间的潜在联系.
研究的目的:
- 调查IBD儿童是否比健康对照群消耗更多的UPF.
- 检查UPF摄入量与儿科IBD疾病活动之间的关联.
- 为了比较患有克罗恩病 (CD) 和性结肠炎 (UC) 的儿童的UPF摄入量.
主要方法:
- 试点横截面病例控制研究,涉及患有IBD的儿童和年龄/性别匹配的健康对照 (HCs).
- 通过两个24小时回忆评估的饮食摄入量.
- 使用NOVA系统量化的UPF摄入量,作为每日总能量摄入量的百分比.
主要成果:
- 与HC相比,患有UC的儿童的UPF摄入量明显高 (MD:10.5%,p=0.02).
- 与HC相比,在患有CD的儿童中 (不包括口服营养支持) 没有发现UPF摄入量的显著差异.
- 接受生物治疗的儿童比接受其他治疗的儿童消耗的UPF少得多 (MD: 8%,p=0.04).
结论:
- 被诊断为IBD的儿童比健康的同龄人消费的超加工食品更高.
- 尽管有诸如克罗恩氏病排除饮食 (CDED) 等饮食建议,但儿科CD患者的UPF摄入量与健康儿童的摄入量没有差异.
- 需要进一步的研究来了解UPF在儿科IBD管理和结果中的作用.
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