患有炎症性肠病的儿科患者的营养方法:治疗,风险和挑战
Maria Elena Capra1, Arianna Maria Bellani2,3, Martina Berzieri2,3
1Pediatrics and Neonatology Unit, Guglielmo da Saliceto Hospital, 29121 Piacenza, Italy.
Nutrients
|November 27, 2025
概括
营养干预对于儿科炎性肠病 (IBD) 是至关重要的. 独家肠道营养 (EEN) 有效地诱导儿童克罗恩病的缓解.
科学领域:
- 儿科胃肠道学和营养学
- 炎症性肠病 (IBD) 管理管理
背景情况:
- 儿科炎症性肠病 (IBD),包括克罗恩病 (CD) 和性结肠炎 (UC),带来独特的挑战,如生长障碍和心理社会困难.
- 营养干预是儿科IBD管理的基石,补充先进的生物和向疗法.
研究的目的:
- 审查当前关于营养策略的证据,以管理儿科IBD.
- 突出各种饮食干预的治疗潜力和局限性.
- 强调营养与药物治疗在多学科方法的整合.
主要方法:
- 关于儿科IBD营养干预的现有文献的叙述性综述.
- 分析评估排他性肠道营养 (EEN),修改饮食 (例如,克罗恩氏病排除饮食 (CDED)) 和一般饮食模式的研究.
主要成果:
- 独家肠道营养 (EEN) 是一线治疗,用于诱导儿科克罗恩病的缓解,其疗效与皮质类固醇相当,对粘膜的愈合和生长有额外的益处.
- 像部分肠道营养和CDED这样的修改饮食方法显示出改善儿科CD的坚持和缓解维护的希望.
- 性结肠炎中营养的作用不太明确,但抗炎饮食可能是有益的.
结论:
- 营养策略,特别是EEN,对于诱导缓解和改善儿科克罗恩病的结果至关重要.
- 个性化,由营养学家监督的营养护理对于减轻与饮食限制相关的缺乏和心理社会压力的风险至关重要.
- 综合营养支持与药物治疗的多学科方法是优化IBD儿童生活质量的关键.
更多相关视频
相关概念视频
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
617
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
617
Inflammatory Bowel Disease IV: Pharmacological Management
450
Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
Pharmacologic...
450
Inflammatory Bowel Disease V: Surgical Management
428
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
428
Inflammatory Bowel Disease I: Ulcerative Colitis
862
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
862
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
461
Crohn's disease is an inflammatory bowel disorder marked by chronic inflammation of the GI tract. Various treatment strategies for Crohn's disease are employed, such as immunomodulatory agents, glucocorticoids, and biologics or anti-TNF therapy. Azathioprine (Imuran), a commonly used immunomodulatory drug for Crohn's disease, is converted in the body to mercaptopurine, which inhibits purine biosynthesis and cell proliferation. Both are utilized in severe cases of Inflammatory Bowel...
461
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
231
Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
231


