婴儿结肠:什么时候怀疑牛奶过敏
Yvan Vandenplas1, Silvia Salvatore2, Mario C Vieira3
1KidZ Health Castle, UZ Brussel, Vrije Universiteit Brussel, 1090 Brussels, Belgium.
Nutrients
|November 27, 2025
概括
牛奶过敏 (CMA) 可能会导致婴儿结肠 (IC),当其他治疗失败并出现过敏症状时. 建议采用诊断性消除饮食,以确认小肠的婴儿的CMA.
科学领域:
- 儿科 儿科 儿科
- 过敏学 过敏学
- 胃肠病学 胃肠病学
背景情况:
- 婴儿结肠炎 (IC) 影响全球20-30%的婴儿,在头三个月内表现为过度哭泣和不安行为.
- 婴儿结肠的根本原因仍然不太清楚,需要进一步调查潜在的促成因素.
- 牛奶过敏 (CMA) 是一个潜在的,虽然尚未完全确立的,导致婴儿的原因.
研究的目的:
- 批判性地审查现有的关于婴儿结肠和牛奶过敏之间的关联的文献.
- 评估诊断方法,以识别患有的婴儿中的CMA.
主要方法:
- 使用MeSH术语对牛奶过敏,食物过敏,结肠和哭泣进行了全面的文献搜索.
- 搜索仅限于自创刊起至2025年6月15日的英语文章,确定了135个相关出版物.
- 专门分析了18项临床试验,重点关注牛奶消除饮食对婴儿结肠的影响.
主要成果:
- 目前尚不确定CMA在婴儿中的作用,尤其是在没有其他过敏症状的情况下.
- 应考虑CMA在持续的婴儿结肠没有响应标准治疗的情况下,特别是如果存在其他过敏表现.
- 诊断性消除饮食,包括排除母牛奶或专用配方,然后再引入,对于诊断CMA至关重要.
结论:
- 目前将CMA与婴儿结肠联系起来的证据有限,这凸显了需要更多研究的必要性.
- 未来的研究应该专注于大型,精心设计的临床试验,以研究母乳养和配方奶粉养的结肠病婴儿的CMA.
- 诊断性消除饮食对于在持续性结肠和疑似过敏反应的婴儿中确认CMA至关重要.
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