更年期过渡和阻塞性睡眠呼吸暂停之间的纵向关联与盐摄入量的效果修改:一项前性队列研究
Sujeong Shin1, Yoonyoung Jang2,3, Yoosoo Chang2,4,5
1Department of Family Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul 03181, Republic of Korea.
Nutrients
|November 27, 2025
概括
高盐摄入量与更年期过渡相结合,显著增加中年妇女阻塞性睡眠呼吸暂停 (OSA) 的风险. 减少饮食盐可以帮助缓解更年期期间的风险.
科学领域:
- 内分泌学 在内分泌学.
- 睡眠医学 睡眠医学
- 营养科学 营养科学
背景情况:
- 高盐摄入量与阻塞性睡眠呼吸暂停 (OSA) 风险的增加有关,通过液体保留和气道狭窄.
- 更年期过渡与可能影响OSA风险的生理变化有关.
研究的目的:
- 调查饮食盐的摄入量是否会改变更年期过渡和OSA风险之间的关联.
- 探索盐摄入量和更年期阶段对OSA风险的协同效应.
主要方法:
- 对2572名年龄在42-52岁之间的女性进行了长度研究,从2014年至2024年进行了跟踪.
- 使用STOP-Bang问卷与调整的BMI值进行评估的OSA风险.
- 饮食盐摄入量分为三类;使用概括估计方程进行统计分析.
主要成果:
- 与绝经前相比,OSA风险在更年期晚期过渡和更年期后显著增加.
- 高盐摄入量 (第三层) 独立地与增加的OSA风险有关.
- 一个显著的相互作用 (p=0.040) 显示了更年期过渡和OSA之间更强的联系在女性的盐摄入量较高,特别是在早期过渡期间.
结论:
- 更年期过渡和高食盐摄入量协同提高中年妇女的OSA风险.
- 建议在更年期过渡期间对OSA和饮食盐分减少进行有针对性的查.
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