在非小细胞肺癌患者中经历化疗诱导的恶心和吐症状:一种定性研究
Jie Cheng1, Jingjing Xu1, Ruyi Shi1
1Department of Oncology, Shanghai Pulmonary Hospital Affiliated to Tongji University, Shanghai, China.
Medicine
|November 27, 2025
概括
化疗诱导的恶心和吐 (CINV) 显著影响非小细胞肺癌患者,造成痛苦和知识不足. 解决这些患者的经验对于改善护理和治疗合规性至关重要.
科学领域:
- 在瘤学瘤学.
- 患者体验研究 研究研究
- 质量健康研究 质量健康研究
背景情况:
- 化疗引起的恶心和吐 (CINV) 是癌症患者普遍出现的不良反应.
- CINV对患者的生活质量,营养状况和治疗坚持有负面影响.
- 了解患者的经验对于改善癌症护理标准至关重要.
研究的目的:
- 在非小细胞肺癌患者中探索化疗诱导的恶心和吐 (CINV) 的感觉和经验.
- 从患者的角度确定与CINV相关的关键主题.
- 为了解决CINV管理中以患者为中心的干预措施的发展.
主要方法:
- 使用半结构面试的定性研究方法.
- 53名非小细胞肺癌患者的有目的抽样.
- 使用Colaizzi的7步分析框架进行数据分析.
主要成果:
- 所有患者都出现了恶心 (100%),有13.2%的人报告吐,在化疗的第五天左右达到顶峰.
- 出现了四个主要主题:CINV严重程度的变化,预防/治疗知识不足,自我感知的负担增加,社会支持不足.
- 这些患者的整体CINV体验具有挑战性,需要更大的社会,医院和家庭支持.
结论:
- 非小细胞肺癌患者当前的CINV经验需要紧急关注和全面支持.
- 需要以患者为中心的健康教育干预措施,以赋予患者管理CINV症状的权力.
- 更好地了解患者的观点可以提高医疗保健专业人员在化疗期间支持患者的能力.
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