对阿弗拉托克辛和肝癌之间的相关性进行了图书统计分析
Zheng Liu1, Bao-Chen Zhu1, Chun-Miao Xue2
1Department of Pharmacy, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Medicine
|November 27, 2025
概括
非洲毒素暴露是肝癌的关键风险因素. 研究表明,青毒素会导致肝损伤和促进癌症,特别是与乙型肝炎病毒 (HBV) 联合感染. 预防策略至关重要.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 毒理学 毒理学 毒理学
- 在瘤学瘤学.
背景情况:
- 阿弗拉托克辛是肝癌的重要危险因素.
- 了解阿弗拉托克辛在肝癌中的作用对于开发向疗法至关重要.
- 阿弗拉托克辛诱导肝癌的确切机制仍在研究中.
研究的目的:
- 分析当前关于阿弗拉托克辛诱导的肝癌的研究进展.
- 确定该领域的前沿研究方向.
主要方法:
- 从2014年到2024年,对597项研究进行了文献计量分析.
- 使用了Web of Science,VOSviewer,CiteSpace和R软件进行数据检索和分析.
- 包括原始研究和关于亚毒素和肝癌的评论.
主要成果:
- 美国和中国是主要的贡献者,有597项研究由3228名作者发表.
- 关键的研究领域包括阿弗拉托克辛暴露和癌症进展,肝毒性机制,与HBV的联合作用和预防策略.
- 非洲毒素诱导肝毒性,免疫毒性,改变基因表达,并在肝癌发生过程中与HBV协同作用.
结论:
- 关于偏素与肝癌之间的联系的研究正在快速进展.
- 阿弗拉托克辛在肝癌的发病过程中起着关键作用.
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