在2只狗中,与大肠杆菌相关的马洛普拉基亚
Haley E Dodson1, Paula R Giaretta2, Kellyn E McNulty2
1Departments of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX, USA.
马拉科普拉基亚是一种罕见的颗粒状疾病,在两只狗的髓中发现了由大肠杆菌引起的复发性尿路感染. 组织病理学证实了这种情况,表明可能与老犬的潜在内分泌病变有关.
科学领域:
- 兽医病理学 兽医病理学
- 狗医疗 狗医疗 狗医疗
- 颗粒状疾病 颗粒状疾病
背景情况:
- 马拉科普拉基亚是一种不常见的颗粒状细胞性疾病,通常影响尿膀.
- 它还可以影响其他器官,如泌尿器官,胃肠道和淋巴结.
- 这份报告详细介绍了狗髓中罕见发生的马拉科普拉基亚病例.
研究的目的:
- 描述两例影响髓的犬类马拉科普拉基亚病例.
- 为了确定脏 malakoplakia 的致病原体和组织学特征.
- 为了探索潜在的诱导因素,这种情况在狗.
主要方法:
- 尸检查和脏和膀组织的组织病理学检查.
- 染色技术包括周期酸 (PAS),·科萨 (von Kossa) 和普鲁士蓝.
- 光 in situ 杂交和/或免疫组织化学检测大肠杆菌.
主要成果:
- 两只狗在髓中呈现马拉科普拉基亚,与复发的大肠杆菌尿路感染有关.
- 组织学发现揭示了含有迈凯利斯-古特曼体的泡性巨细胞.
- 大肠杆菌被证实在受影响组织中的巨细胞内存在.
结论:
- 马拉科普拉基亚可能发生在狗髓中,与典型的膀呈现不同.
- 大肠杆菌被认为是致病原体.
- 潜在的内分泌病变可能会使老年狗易患马拉科普拉基亚.
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