可重复使用的医疗器械和植入物的高效和安全的灭菌方法是轻微酸性电解水
Yan Zhang1,2, Chengcheng Meng1, Wenze Ma1
1Key Laboratory of Livestock Infectious Diseases, Ministry of Education, Shenyang Agricultural University, Shenyang, China.
Biofouling
|November 27, 2025
概括
微酸电解水 (SAEW) 有效地消除医疗器械上的细菌生物膜. 这种新型消毒剂迅速消灭细菌和生物膜,证明了卓越的性能和材料兼容性.
科学领域:
- 生物医学工程 生物医学工程
- 微生物学 微生物学
- 材料科学 材料科学 材料科学
背景情况:
- 医疗器械上的生物膜污染构成严重的感染风险.
- 目前的消毒剂在有效性或材料兼容性方面可能存在局限性.
研究的目的:
- 评估微酸电解水 (SAEW) 作为医疗器械和植入物的消毒剂.
- 评估SAEW对细菌生物膜的有效性及其对材料腐蚀的影响.
主要方法:
- 对抗浮游生物细菌和生物膜的SAEW的疗效与NaClO.O.进行了比较.
- 作用机制涉及细胞外聚合物质 (蛋白质和eDNA) 的降解.
- 分析了对细菌形态,基因表达和材料腐蚀的影响.
主要成果:
- SAEW迅速消灭了浮游生物细菌和生物膜,性能优于NaClO.
- SAEW降解了生物膜组件,使其能够透和细菌溶解.
- 在 * Staphylococcus aureus * 和 * Staphylococcus epidermidis * 中,SAEW 降低了关键生物膜相关基因的调节.
- 手术器械上的生物膜在10分钟内被清除.
- 在SAEW中,不钢,合金或黄铜没有显著的腐蚀.
结论:
- 赛具有强大的抗菌和生物膜清除特性.
- SAEW是一种安全有效的医疗器械和植入物消毒剂.
- 在医疗保健机构中,SAEW为感染控制提供了一个有前途的替代方案.
相关概念视频
Methods of Sterilization II: Chemical Methods
8.8K
In healthcare, the chemical method of sterilization uses chemical sterilants to treat surgical instruments and medical supplies to help prevent the transmission of infectious pathogens to patients. Due to heat sensitivity, most medical supplies and equipment should not be exposed to high temperatures. These parts include rubber, plastic, glass, and other similar elements.
Using chemical sterilization rather than heat to clean out equipment is recommended. It eradicates and removes all bacteria,...
Using chemical sterilization rather than heat to clean out equipment is recommended. It eradicates and removes all bacteria,...
8.8K
Methods of Sterilization I: Physical Methods
23.3K
As used in a healthcare facility, sterilization destroys all microorganisms through physical or chemical methods. The physical method includes steam, dry heat, boiling water, and radiation.
Steam sterilization uses non-toxic, low-cost moist heat in the form of saturated steam under pressure, which is fast, microbicidal, and sporicidal, and quickly warms and penetrates fabrics. Autoclaves, or steam sterilizers, expose each item to direct steam contact for a predetermined time at the necessary...
Steam sterilization uses non-toxic, low-cost moist heat in the form of saturated steam under pressure, which is fast, microbicidal, and sporicidal, and quickly warms and penetrates fabrics. Autoclaves, or steam sterilizers, expose each item to direct steam contact for a predetermined time at the necessary...
23.3K
Cleaning, Sterilization, and Disinfection
9.5K
Cleaning, disinfection, and sterilization are the methods that help to break the infection chain and prevent disease.
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
9.5K
Physical Methods for Controlling Microbial Growth: Radiation and Filtration
958
Radiation and filtration are essential tools for microbial control, targeting microorganisms through distinct mechanisms. Radiation eliminates microbes by damaging their DNA, either killing them or inhibiting their growth. Based on wavelength, radiation is classified into two types: nonionizing and ionizing radiation.Non-ionizing radiation, such as UV radiation (200–400 nm), is absorbed by DNA, causing defects that effectively disinfect surfaces, air, and water, including safety cabinets.
958
Chemical Agents for Microbial Control
728
Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
728
Hand hygiene
5.5K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Hand washing...
5.5K


