相关实验视频
Updated: Jan 10, 2026
10:42
Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
Published on: December 31, 2017
17.8K
皮肤刻字图案与儿童口腔疾病之间的关联:系统性审查和元分析
Chhavi Jain1, Azhar Uddin2, Nilima Sharma1
1Department of Dentistry, Hamdard Institute of Medical Sciences and Research, Hakeem Abdul Hameed Centenary Hospital, New Delhi, IND.
Cureus
|November 27, 2025
概括
皮肤刻字图案,如指纹旋转和循环,显示了与儿童口腔健康问题 (如牙损伤和唇裂) 的潜在联系. 这些特征可能是儿童口腔疾病的低成本指标.
科学领域:
- 皮肤病学和口腔健康
- 遗传学和发育生物学
背景情况:
- 皮肤刻字学,即研究表皮脊纹的研究,与口腔-面综合体同时发展.
- 这些模式在整个生命中都是稳定的,使它们成为潜在的发育条件的非侵入性标记.
- 以前的研究表明,皮肤刻字特征与儿童口腔疾病之间可能存在关联.
研究的目的:
- 系统地审查和元分析皮肤刻字特征与三个儿科口腔疾病之间的关联:牙损伤,缺陷和非综合征裂口唇和/或 (NSCL/P).
主要方法:
- 按照PRISMA 2020指南进行系统审查和元分析.
- 搜索了Medline,Ovid,Cochrane CENTRAL和谷歌学者 (1990-2025) 进行横截面和病例对照研究.
- 包括15项研究 (大约. 7,300名儿童) 评估定性 (循环,旋转,弧形) 和定量 (角,脊数) 的皮肤刻字特征.
主要成果:
- 在患有牙损伤的儿童中观察到,牙旋转的频率增加和环的频率降低.
- 与牙腐烂相关的弧度有显著的变化.
- 在患有NSCL/P的儿童中发现了较低的总脊数,较高的a-b脊数和更大的波动不对称性.
- 在缺陷研究中观察到不一致的特定类型的模式转移.
结论:
- 皮肤刻字的特征,特别是旋转,循环和角度,显示出与儿科口腔疾病的潜在关联.
- 这些特征可以作为低成本的指标,虽然不是诊断.
- 需要进一步的大规模,多中心,纵向研究来验证这些发现,解决异质性和潜在偏见.
相关概念视频
01:15Teeth
1.6K
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
1.6K
01:21Tooth Anatomy
2.0K
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
2.0K
01:26Assessment of the Mouth
974
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
974
01:11Oral Cavity
2.9K
The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
2.9K