假肢关节感染的单阶段和两阶段修订的长期结果:一个回顾性,观察性队列研究
Aishwarya Ghosh1, Suroosh Madanipour1, John Stammers1,2
1Trauma & Orthopaedics St George's University Hospitals NHS Foundation Trust.
Orthopedic reviews
|November 27, 2025
概括
假肢关节感染 (PJI) 的单阶段复查显示,在精心挑选的患者中,感染清除和死亡率与两阶段复查相似. 这支持PJI治疗中日益使用单阶段程序.
科学领域:
- 整形外科手术 整形外科手术
- 传染病管理 传染病管理
- 关节整形术的结果
背景情况:
- 假肢关节感染 (PJI) 是整体关节整形术的严重并发症.
- 对比单阶段和两阶段的修订程序对于优化患者的治疗结果至关重要.
- 了解感染清除和治疗失败率是PJI管理的关键.
研究的目的:
- 为了比较PJI的单阶段和两阶段修订的长期结果.
- 评估人口统计学上相似的患者队列中的感染清除率和治疗失败率.
- 评估PJI管理中单阶段修订的有效性.
主要方法:
- 在高等推中心进行回顾性队列研究 (2011-2021年).
- 包括PJI患者进行单阶段或两阶段修订,随访时间≥2年.
- 分析感染清除和治疗失败作为主要结果.
主要成果:
- 在单阶段 (n=50) 中,感染清除率为96%;在双阶段 (n=25) 中,清除率为92% (p=0.624).
- 治疗失败率低且相似:4% (单阶段) 与8% (双阶段).
- 在各组之间,所有原因的5年和10年死亡率相似.
结论:
- 在选择的患者中,单阶段修订显示了PJI的两阶段修订和可比的感染清除.
- 结果支持在适当选择的个体中增加PJI单阶段修订的使用.
- 长期结果和死亡率相似,有利于单阶段修订的效率.
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