探索和比较大型语言模型的使用,以支持骨质疏松症健康咨询
1Department of Orthopedics, The First People's Hospital of Lianyungang, Lianyungang, Jiangsu, People's Republic of China.
Clinical interventions in aging
|November 27, 2025
概括
在骨质疏松症问题上的三个大型语言模型 (LLM) 中,ChatGPT-4o显示出最好的医学准确性和内容全面性. 专家监督对于这些AI工具的安全临床使用至关重要.
科学领域:
- 人工智能在医学中的应用
- 医疗信息学 医疗信息学
- 整形外科 整形外科 整形外科
背景情况:
- 大型语言模型 (LLM) 越来越多地被用于医疗保健应用.
- 评估LLM的临床实用性需要对其准确性和全面性的严格评估.
- 骨质疏松症患者教育为人工智能驱动的支持提供了一个潜在的领域.
研究的目的:
- 为了比较三个LLM在回答骨质疏松症相关问题的医学准确性和内容全面性.
- 评估LLMs在骨质疏松症临床支持中的潜在作用.
主要方法:
- 对三个LLM提出了六个领域的25个骨质疏松问题.
- 五位高级骨科医生评价了响应的准确性 (5分利克尔特尺度).
- 可接受的答案被评估为内容的全面性;统计分析包括Kruskal-Wallis和Dunn的测试.
主要成果:
- 聊天GPT-4o实现了最高的准确性 (中位数:4.6),显著超过双子-2.5 Pro (p=0.039) 和DeepSeek-R1 (p<0.001).
- 聊天GPT-4o和双子-2.5 Pro显示了类似的内容全面性 (中位数:4.4),优于DeepSeek-R1 (中位数:4.2).
- 双子-2.5 Pro提供了用户友好的语言,但有时缺乏临床深度;DeepSeek-R1提供引用,但不一致.
结论:
- 在骨质疏松症中,LLM显示出患者教育的潜力.
- 在评估的模型中,ChatGPT-4o表现出最平衡和最可靠的性能.
- 专家医疗监督对于LLMs在医疗保健中安全有效地整合至关重要.
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