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膜蛋白-连接体相互作用研究的计算工作流程:专注于α5-含GABA (A) 受体的α5-含GABA (A) 受体

Syarifah Maisarah Sayed Mohamad1, Khairul Bariyyah Abd Halim2, Azzmer Azzar Abdul Hamid3

  • 1Department of Neurosciences, School of Medical Sciences, Universiti Sains Malaysia Health Campus, Kota Bharu, Kelantan, Malaysia.

Bio-protocol
|November 27, 2025
PubMed
概括

这项研究引入了一种计算工作流程,用于分析膜蛋白-连接体相互作用,这对于神经药理学和药物发现至关重要. 该方法使用同质模型,对接和分子动力学来研究像GABA (A) 受体这样的目标.

关键词:
在GABA (A) 受体中,GABA (A) 受体是膜蛋白建模的模型分子对接是分子对接.分子动力学模拟模型受体连接体相互作用

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